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New study: LIB-01 assumed to be the next generation of potency drugs

Uppsala, November 15, 2022. Dicot's latest study of the mechanism of action of LIB-01, i.e., how the drug affects the body to achieve the desired effect, shows that it differentiates from today's potency drugs. This means that LIB-01 can be assumed to represent a new generation of potency drugs.

Dicot is developing a modern potency drug to treat erectile dysfunction and premature ejaculation better than existing medicines. As part of the long-term development work, studies are underway to map LIB-01's mechanism of action - that is, how the drug affects underlying processes in the body so that the desired effect occurs.

Results from a recent ex vivo study show that the mechanism of action of LIB-01 differentiates from today's potency drugs such as e.g., Viagra. These are significant results as today's potency drugs, with their mechanism of action, do not work optimally for all patients whereof approximately 35% do not have sufficient effect and many report unwanted side effects.

"The fact that we now can postulate that the mechanism of LIB-01 differentiates from current ED drugs is of great importance, and an indication that LIB-01 may represent a new generation of ED drugs", comments Professor Francois Giuliano, urologist specialized in sexual medicine and founder of Pelvipharm.

"With a different mechanism of action than today's drugs, we have a great potential to show that LIB-01 can treat sexual dysfunctions better than current treatments," says Elin Trampe, CEO at Dicot.

For further information, please contact:

Elin Trampe, CEO
Tel: +46 739 80 14 08
elin.trampe@dicot.se

About Dicot AB

Dicot is developing the drug candidate LIB-01, which will be a potency agent to better treat erectile dysfunction and premature ejaculation. The ambition is to create a drug with significantly longer effect and far fewer side effects, compared to those on the market. Today, at least 500 million men suffer from these sexual dysfunctions and the market is valued at SEK 50 billion. Research and development are conducted under own auspices up to phase 2 studies. Thereafter, Dicot's intention is to form strategic alliances, or alternatively carry out a trade sale, with larger, established pharmaceutical companies to be able to introduce LIB-01 on the world market.

Dicot is listed on Spotlight Stock Market and has approximately 3,300 shareholders. For more information, please visit www.dicot.se.

2023-02-27
Regulatory

Press release: Uppsala, February 27, 2023. Dicot AB (publ) hereby publishes its year-end report for the period January - December 2022 and for the fourth quarter. The year-end report is available  as an attached document and on the company's website www.dicot.se. Below is a summary of the report.
 

Fourth quarter 2022

  • Net sales amounts to KSEK 0 (0)
  • Earnings after financial items amounts to KSEK -8,604 (-8,408)
  • Earnings per share amounts to SEK -0.06 (-0.10)

January - December 2022

  • Net sales amounts to KSEK 0 (0)
  • Earnings after financial items amounts to KSEK -31,756 (-27,175)
  • Earnings per share amounts to SEK -0.26 (-0.42)
2022-11-01
Regulatory

Press release: Uppsala, November 1, 2022. The correction is to inform that the previous press release regarding Dicot AB's (publ) interim report for January - September 2022 should not have been marked with the MAR label.

2022-11-01
Regulatory

Press release: Uppsala, November 1, 2022. A summary of the Interim report January - September 2022, for Dicot AB (publ) is now available on the company website www.dicot.se.

2022-10-11
Regulatory

Dicot reports that the preclinical toxicology studies that are now being conducted, so far show that the drug candidate LIB-01 has a good safety profile.

2022-08-25
Regulatory

Press release: Uppsala, August 25, 2022. A summary of the Interim report January - June 2022, for Dicot AB (publ) is now available on the company website www.dicot.se.

2022-06-29
Regulatory

Press release: Uppsala, June 29, 2022. Dicot AB is developing a new potency drug aiming at becoming the first choice of treatment. The company announces today that the newly developed oral formulation demonstrates good results in a recently conducted efficacy study.

2022-06-17
Regulatory

Press release: Uppsala, June 17, 2022.

Dicot AB (publ) ("Dicot" or the "Company") announces the outcome regarding exercising of warrants of series TO 3. Holders of warrants exercised 34,202,814 warrants, corresponding to approximately 90 percent of the number of outstanding warrants, for subscription of 34,202,814 shares at a subscription price of SEK 0.29 per share. Through the exercise of the warrants, Dicot will receive approximately SEK 10 million before issue costs.

2022-06-13
Regulatory

Press release: Uppsala, June 13, 2022. The company announces that members in the board and management are increasing their shareholding in the company.

2022-05-29
Regulatory

Press release: Uppsala, May 29, 2022.

During the fourth quarter of 2021, Dicot AB (publ) (``Dicot`` or ``the Company``) conducted a rights issue of units, with one (1) unit consisting of three (3) new issued shares and three (3) free-of-charge warrants of series TO 3 (previously also named series 2021/2022). Those who subscribed for units during the subscription period between October 12, 2021, and October 27, 2021, therefore obtained three (3) additional warrants of series TO 3 per unit subscribed. Each warrant of series TO 3 entitles the holder to subscribe for one (1) new share in Dicot. The subscription price for subscription of shares using warrants will correspond to 70 percent of the average volume-weighted price of the Company's share according to Spotlight Stock market's official list during the period from May 16, 2022, up to and including May 27, 2022. However, the subscription price shall not be higher than 1.50 SEK or lower than 0.125 SEK (corresponding quota value of the Company's share). The average volume-weighted price of the Company's share during the measurement period amounted to approximately 0.41 SEK, hence, the subscription price has been set to 0.29 SEK per share.

2022-05-06
Regulatory

Press release: Uppsala, May 6, 2022. A summary of the Interim report January - March 2022, for Dicot AB (publ) is now available on the company website www.dicot.se 

First quarter 2022

  • Net sales amounts to kSEK 0 (0)
  • Earnings for the period amounts to kSEK -9,346 (-8,468)
  • Earnings per share SEK -0.09 (-0.19)
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